The invention provides an intelligent express box with an encrypted keyboard, and relates to an intelligent express box and an intelligent self-picking-up cabinet, and in particular relates to self-service equipment of a logistics terminal and intelligent logistics equipment. The intelligent express box comprises a control main board, an electronic lock, a power supply and a cabinet body; the power supply is connected with the control main board and the electronic lock; the intelligent express box comprises an encrypted keyboard; and the encrypted keyboard is connected with the control main board. The encrypted keyboard is arranged on the cabinet body. The encrypted keyboard is a metal keyboard. The intelligent express box comprises a display screen, and the display screen is connected with the main board and the power supply. The intelligent express box comprises an image pick-up module, and the image pick-up module is connected with the main board and the power supply. The intelligent express box comprises a two-dimension code identifying module, and the two-dimension code identifying module is connected with the control main board.